Curriculum Vitae

Michael L. Hayes, PhD

271 La Kretz Hall   ▪   CSULA   ▪   Los Angeles, CA 90034

(323) 343-2144   ▪    mhayes3 (at) calstatela.edu

Summary of Qualifications

I teach fundamentals of biochemistry and plant molecular biology to undergraduate and graduate students. I work with students to translate scientific concepts into a defined research program. Currently my laboratory is researching the structure and function of a C-to-U RNA editing complex including an enzyme called the DYW-deaminase.

Education

Ph.D. Biochemistry, Molecular & Cellular Biology                                Mentor:  Prof. Maureen Hanson, Ph.D.

Cornell University, Ithaca, NY                                                                                                 2002 – 2008

B.S. Agricultural Biotechnology & Biology                                                Mentor:  Prof. Glenn Collins, Ph.D.

University of Kentucky, Lexington, KY                                                                                     1998 – 2002

Research Experience

Assistant Professor

California State university, Los Angeles, CA                                                                            2015– Present

Assistant Project Scientist

University of California Irvine, Irvine, CA                                                                                   2013–2015                                                                                                     

Post-Doctoral Scholar                                                                                                             

University of California Irvine, Irvine, CA                                                                                   2009– 2013

Post-doctoral Scholar

University of California Santa Barbara, Santa Barbara, CA                                                        2008– 2009

Ph.D. Candidate

Cornell University, Ithaca, NY                                                                                                2002 – 2008

Teaching Experience and Community Involvement

Faculty Co-Sponsor of the Biochemistry Club

California State university los angeles, Los Angeles                                                                 2018 – Present

Assistant Professor of Biochemistry

California State university los angeles, Los Angeles                                                                 2015 – Present

Community Gardener

Solano Canyon Community Garden and Urban Farm, Los Angeles, CA                                     2010 – 2015

Research Mentor

University of California Irvine, Irvine, CA                                                                                   2009 – 2015

Graduate / Undergraduate Mentor     

Cornell University, Ithaca, NY                                                                                                 2004 – 2007                                                                                            

Teaching Assistant        

Cornell University, Ithaca, NY                                                                                                 2002 – 2003     

Editor / Webmaster / Board Member                                          

Liberty Hyde Bailey Garden Club, Ithaca, NY                                                                           2005 – 2007       

Academic Honors

Poster Award for Outstanding Poster Presentation

Gordon Research Conference: RNA Editing, Ventura, CA                                                         2007

Predoctoral NIH Training Fellow

Cornell University, Ithaca, NY                                                                                                 2005 – 2006

Invited Speaker

16th Penn State Plant Symposium, Penn State University, University Park, PA                          2006

Award for Outstanding Presentation

CSPP/SCPV 2004 Annual Meeting, Guelph, ON, Canada                                                         2004

Astronaut Scholarship

University of Kentucky, Lexington, KY                                                                                    2000 – 2002

Conferences and Meetings

Invited Speaker

Gordon Research Conference: Chloroplast Biotechnology                                                            2019

Poster Presenter     

Gordon Research Conference: Mitochondria and Chloroplasts, Lucca, Italy                                 2018

Poster Presenter     

23rd Annual RNA Society Meeting, Berkeley, CA                                                                           2018

Poster Presenter                    

Western Divisional Meeting of the American Society of plant biologists, Fullerton, CA                 2018

Poster Presenter                                                

Gordon Research Conference: Chloroplast Biotechnology, Ventura, CA                                       2017

Poster Presenter        

Gordon Research Conference: Chloroplast Biotechnology, Ventura, CA                                       2015

Invited Speaker

3rd International symposium on chloroplast genomics and genetic engineering, Rutgers, NJ          2013

Poster Presenter

Gordon Research Conference: Mitochondria & Chloroplasts, Smithfield, RI                                  2012

Publications

Sandoval, R; Boyd, R; Kiszter, AN; Mirzakhanyan, Y; Santibańez, P; Gershon, P; Hayes, ML (2019) Stable native RIP9 complexes associate with C-to-U RNA editing activity, PPRs, RIPs, OZ1, ORRM1, and ISE2. The Plant J. in press

Diaz MF, Bentolila S, Hayes ML, Hanson MR, Mulligan RM. A protein with an unusually short PPR domain, MEF8, affects editing at over 60 Arabidopsis mitochondrial C targets of RNA editing. Plant J. 2017. doi: 10.1111/tpj.13709. PubMed PMID: 29035004.

Hayes ML, Dang KN, Diaz MF, Mulligan RM. A conserved glutamate residue in the C-terminal deaminase domain of pentatricopeptide repeat proteins is required for RNA editing activity. Journal of Biological Chemistry. 2015 290:10136-42.

Hayes ML, Giang K, Berhane B, Mulligan RM. Identification of two pentatricopeptide repeat genes required for RNA editing and zinc binding by C-terminal cytidine deaminase-like domains. Journal of Biological Chemistry. 2013 288: 36519-29.

Hayes ML, Giang K, Mulligan RM. Molecular evolution of pentatricopeptide repeat genes reveals truncation in species lacking an editing target and structural domains under distinct selective pressures. BMC Evolutionary Biology. 2012 12: 66.

Hayes ML, Mulligan RM. Pentatricopeptide repeat proteins constrain genome evolution in chloroplasts. Molecular Biology and Evolution. 2011 28(7): 2029-39.

Hayes ML, Hanson MR. High conservation of a 5’ element required for RNA editing of a C target in chloroplast psbE transcripts. Journal of Molecular Evolution.  2008 67: 233-45.

Heller WP, Hayes ML, Hanson MR. Cross-competition in editing of chloroplast RNA transcripts in vitro implicates sharing of trans-factors between different C targets. Journal of Biological Chemistry. 2008 283: 7314-7319.

Hayes ML and Hanson MR. Assay of editing of exogenous RNAs in chloroplast extracts of Arabidopsis, maize, pea, and tobacco. Methods of Enzymology. 2007 424: 459-482.

Hayes ML and Hanson MR. Identification of a sequence motif critical for editing of a tobacco chloroplast transcript. RNA. 2007 13: 281-288.

Hayes ML, Reed ML, Hegeman CE, and Hanson MR. Sequence elements critical for efficient RNA editing of a tobacco chloroplast transcript in vivo and in vitro. Nucleic Acids Research. 2006 34: 3742-3754.

Hegeman CE, Hayes ML, and Hanson MR. Substrate and cofactor requirements for RNA editing of chloroplast transcripts in Arabidopsis in vitro. Plant J. 2005 42: 124-132.