PowerPoint Presentation - Differential regulation of Id1, Id2, andTwist in myogenesis and osteogenesis

Id-1
oBelongs to the Id protein family (Id-1,2, 3, 4)
oHLH protein
oInhibitor of differentiation
oPreferentially dimerizes with bHLHproteins
oActs in a dominant negative fashion
oPrevents bHLH proteins from formingdimers with other bHLH proteins
oPrevents bHLH proteins from bindingDNA
oIs differentially regulatedduring differentiation of mesenchymal stem cells to different cell types
o
o
o
o